In addition to the presence of 5 or more symptoms, one of which being depressed mood or anhedonia, being present during the same two week period, all of the following are required to meet the diagnostic criteria of MDD except what?
a) Symptoms cause clinically significant distress or impairment
b) The episode is substance-induced
c) Patient's symptoms are not explained by Schizophrenia or other psychotic disorder
d) There has NEVER been a manic or hypomanic episode
Answer: B
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